
Patch-Clamp Recordings
October 13, 2020The brain is composed of a wide array of interconnected neurons, including both excitatory principal cells and a diverse assortment of... Read More

The epileptic zebrafish model
July 2, 2020The optical transparency and small brain sizes of larval zebrafish have enabled unprecedented access to single-cell neural dynamics across the whole... Read More

Octopus Research
April 7, 2020Cephalopods, including the cuttlefish, octopus, and squid, possess one of the most advanced nervous systems among invertebrates. With their advanced nervous systems,... Read More

Juxtacellular Recordings
December 18, 2019Pyramidal cells, the principal excitatory cells of the hippocampus, are under the control of a remarkably diverse set of inhibitory interneurons. These interneurons show... Read More

Behavioral Experiments
December 18, 2019A major impediment to progress towards reproducible, rigorous preclinical research in epilepsy is that current experimental approaches often require prohibitively time... Read More
Multi-electrode Array Recording
December 18, 2019We use high-density silicon probes in the hippocampus and related circuits to record from single neurons and monitor the local field... Read More

Closed-Loop Optogenetics
December 18, 2019Optogenetics is a control technology that allows the fast, selective excitation or inhibition of specific neurons with light by expressing light-sensitive... Read More

In-vivo Imaging with Miniscopes
December 18, 2019To monitor the activity of specific cells during unrestricted behavior, we use open-source head-mounted miniscopes developed at UCLA (miniscope.org) to measure... Read More

In-vivo Calcium Imaging
December 18, 2019We’re using 2-photon microscopy to record neuronal activity with single-cell resolution in the hippocampus of awake, behaving mice. Taking advantage of... Read More
Computational Modeling
December 18, 2019The hippocampal circuits that store and recall spatial information are comprised of diverse cell types, each exhibiting distinct dynamics and complex... Read More